Cart
sales@molnova.com
NSC 86429
CAS No. 5812-07-7
NSC 86429 ( SU-4312; SU 4312; SU4312. DMBI; NSC 86429 )
Catalog No. M17109 CAS No. 5812-07-7
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
|
| 5MG | 72 | In Stock |
|
| 10MG | 125 | In Stock |
|
| 25MG | 232 | In Stock |
|
| 50MG | 363 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNSC 86429
-
NoteResearch use only, not for human use.
-
Brief DescriptionSU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively).
-
DescriptionSU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
-
SynonymsSU-4312; SU 4312; SU4312. DMBI; NSC 86429
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetAkt
-
RecptorPDGFR; VEGFR
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number5812-07-7
-
Formula Weight264.33
-
Molecular FormulaC17H16N2O
-
Purity98%
-
Solubility——
-
SMILESCN(C)C1=CC=C(C=C1)/C=C\2/C3=CC=CC=C3NC2=O
-
Chemical Name3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li Y, et al. Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation. Endocrinology. 2015 Nov;156(11):4257-68.
molnova catalog
related products
-
Ch-319
Ch-319 (Ch319) is a triphenyltin (IV) carboxylate derivative that modulates AKT/FOXO3a signaling and inhibits progression of prostate cancer.
-
AKT Kinase Inhibitor
An Akt kinase inhibitor.
-
Demethyleneberberine
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.
