Cart
sales@molnova.com
Home - Products - Cytoskeleton/Cell Adhesion Molecules - Akt - NSC 86429

NSC 86429

CAS No. 5812-07-7

NSC 86429 ( SU-4312; SU 4312; SU4312. DMBI; NSC 86429 )

Catalog No. M17109 CAS No. 5812-07-7

SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 42 In Stock
5MG 72 In Stock
10MG 125 In Stock
25MG 232 In Stock
50MG 363 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    NSC 86429
  • Note
    Research use only, not for human use.
  • Brief Description
    SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively).
  • Description
    SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
  • Synonyms
    SU-4312; SU 4312; SU4312. DMBI; NSC 86429
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    PDGFR; VEGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    5812-07-7
  • Formula Weight
    264.33
  • Molecular Formula
    C17H16N2O
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CN(C)C1=CC=C(C=C1)/C=C\2/C3=CC=CC=C3NC2=O
  • Chemical Name
    3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li Y, et al. Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation. Endocrinology. 2015 Nov;156(11):4257-68.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Chromeceptin

    Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.

  • Recilisib

    Recilisib is a radioprotectant,can activate AKT, PI3K activities in cells.

  • PTP1B-IN-2

    PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).

Sign In Join Free